Magic mushrooms will be a lowest law enforcement priority in Portland beginning October 30, Los Angeles officials warn of a dangerous new synthetic opioid, and more.

Marijuana Policy
Sixty-Two Massachusetts Lawmakers Oppose Marijuana Repeal Initiative. Led by the state's top legislative leaders—House Speaker Ronald Mariano (D) and Senate President Karen Spilka (D)—62 state legislators, including Republicans, came out Friday against Question 8, Marijuana Moment reported. That initiative would roll back the state's commercial legalization of marijuana by barring adult-use sales and ending home cultivation but would still allow for personal possession and would keep the state's medical marijuana program intact. Opponents cited jobs, tax revenue, racial disparities in enforcement, and the prospect of returning sales to the unregulated market. The endorsements add legislative leaders and dozens of state legislators to the campaign against repeal. Recent polls cited by Marijuana Moment show majorities opposing Question 8.
Medical Marijuana
South Dakota Medical Marijuana Advocates Challenge Oversight Committee’s Speaker Choices. South Dakota Searchlight reports that the state's Medical Marijuana Oversight Committee took flak from industry representatives over the committee's predilection for inviting out-of-state foes of the state's voter-approved medical marijuana program to make presentations before it. Ned Horsted, the operator of 605 Cannabis in the southeast part of the state, pointed to invites to a Harvard professor and a Colorado doctor who oppose marijuana rescheduling, as well as a presentation from the leading anti-marijuana advocate in the country, Kevin Sabet of Safe Approaches to Marijuana (SAM). "You’ve done quite the job once again in stacking the committee with anti-cannabis individuals from out of state," said Horsted. "The agendas produced by this committee show evidence of a two-year war on patients, industry and, at times, the Department of Health."
Committee chair Rep. Josephine Garcia (R) defended the speakers, claiming they provided a way to learn from other states. The House passed an effort to abolish the committee, which includes legislators and representatives of healthcare professions, patients, and law enforcement, but the Senate killed it in the last session.
Kentucky Has Medical Marijuana Dispensaries in Every Licensing Region. Marijuana Moment reports that Gov. Andy Beshear (D) announced last Friday that at least one dispensary now operates in each of the state's 11 licensing regions. A dispensary opening in Sunnyside, Floyd County, marked that milestone. The state's first dispensary opened in December 2025, nearly a year after the medical marijuana law took effect. Twenty-six dispensaries statewide now serve more than 28,000 patients.
Nebraska Proposes Medical Marijuana Fees and New Patient Requirements. The Nebraska Examiner reports that the state's Medical Cannabis Commission is proposing a $5,000 application fee, annual licensing fees of $10,000 to $28,500, and a $13,000 seed-to-sale tracking fee for medical marijuana operators. Under the proposal, health practitioners would have to swear they did an in-person appointment before recommending medical marijuana, and they would have to notify the commission if they learn a patient is pregnant. The public comment period ended last week, but the commission's website has the official proposed regulations. They still require further review and executive branch approval.
Drug Policy
GI-TOC Report Examines Regional Differences in North America’s Synthetic Drug Supply. In its premier issue, the Global Initiative Against Transnational Organized Crime’s North American Fentanyl and Synthetic Drugs Monitor argues that drug-policy responses need to account for sharply different local supplies. The findings caution against treating fentanyl as a uniform market because users face additional risks from unexpected ingredients, and the mixtures vary across places and over time. The report draws on drug-checking results, official data, and field research to describe regional differences in the prevalence of various substances detected. It also looks at decades of Mexican military anti-drug activity to provide context for the battle against synthetic drug production, and it warns that "The franchise model used by the Cartel Jalisco Nueva Generacion severely limits the impact of seizing labs."
RAND Researcher Urges Clearer Definitions in Drug Decriminalization Debate. In a June analysis published by the Brookings Institution, RAND Drug Policy Research Center codirector Beau Kilmer argues that evaluating drug decriminalization requires distinguishing the removal of criminal penalties from reduced enforcement and legal production or sales. And he cautions against attributing outcomes of larger reform packages to decriminalization. He notes that in Portugal, decriminalization came with expanded services, and in Oregon, Measure 110 decriminalization was paired with changes in treatment funding, which lagged behind. Kilmer's analysis offers a way to assess competing claims about reform: specify which policies changed, when they changed, and which effects the evidence can actually isolate.
Psychedelics
Portland Approves Lower Enforcement Priority for Natural Psychedelics. On September 30, the city council approved an ordinance making noncommercial personal use of naturally occurring psychedelic plants and fungi a low law-enforcement priority, according to the city’s official record. The ordinance goes into effect on October 30. Supporters argued that reducing the risk of getting caught can support education and harm reduction. Law enforcement will continue to act against illegal sales, and sanctions will remain for impaired driving and other unsafe conduct. The ordinance cannot and does not repeal state or federal drug prohibitions.
New Mexico Psilocybin Rules Draw Objections Over Patient Access. Jack Gorsline of Psychedelic State(s) of America reports that proposed rules for the state's medical psilocybin program came under fire from advocates, lawmakers, and health practitioners at a hearing earlier this month. Advocates, lawmakers, and health practitioners criticized in-person examination requirements, patient approval delays, staffing mandates, and provisions requiring landlord permission for treatment in rented homes, with state Sen. Jeff Steinborn (D), the law's principal sponsor, objecting to giving landlords a veto over the care of homebound patients. While some clinicians praised proposed training and supervision standards, they called for fewer administrative barriers. The proposed rules are still in draft form; no final decision on them has been made.
Harm Reduction -- Medication Assisted Treatment
Massachusetts Mobile Methadone Services Ease Travel Burdens, Patients Report. The Institute for Community Health issued a report on October 8 that found patients and staff alike reported shorter travel times and greater privacy using mobile methadone services. The state now has four mobile methadone units, including two in rural areas. The units were launched with funding from the Bureau of Substance Addiction Services and operate under their home opioid treatment programs’ licenses. They deliver methadone from established opioid treatment programs to pre-approved community locations, reducing the need for patients to travel to distant clinics. These initial findings come from interviews; researchers will also review medical records to better assess the services' scope and impact on treatment.
New South Wales Prepares New Methadone and Buprenorphine Treatment Standards. NSW Health has released new standards for the state's Opioid Treatment Program, effective November 5. The department says the changes are designed to strengthen patient safeguards and simplify legal requirements for opioid prescribers. The new standards are mandatory for practitioners, pharmacists, and opioid-assisted treatment facilities. A webinar scheduled for October 20 will introduce the prescribing guide.
Nepal Opioid Treatment Assessment Finds Wide Gaps in Access. Harm Reduction International and local partners reported on October 2 that opioid agonist therapy is reaching only 13 percent of its target population in Nepal, far below the government goal of 40 percent. That therapy is available in only 10 of the country's 77 districts. Researchers identified problem areas, including a lack of take-home doses, hidden patient costs, limited funding, outdated policies, and restrictive service models. They recommended changes to make treatment more accessible, especially for women and young people, and to sustain domestic spending. This analysis is based on coverage estimates, not a new nationwide patient census.
Ontario Approves New Restrictions on Safer Supply Prescribing. The College of Physicians and Surgeons of Ontario, which regulates doctors in the province, announced new restrictions on safer supply prescriptions on October 13 "to reduce the risk of diversion and strengthen oversight of prescribing practices," according to a press release from the group. The new restrictions require that physicians only prescribe safer supply medication in conjunction with opioid agonist therapy (OAT), support supervised consumption of all safer supply medication by requiring physicians to clearly identify “safer supply” and specify "no carries" (no take-home doses) on prescriptions, and require a comprehensive in-person clinical assessment at least monthly for patients receiving safer supply medication. The college said it will enforce the new restrictions beginning November 16.
[Editor’s note: Vancouver’s DULF compassion club offered tested drugs at cost without prescriptions. Authorities shut it down and prosecuted its founders, who then won a constitutional challenge September 29. The court stayed their proceedings but delayed invalidating the prohibition for six months. - DB]
Harm Reduction - Drug Checking
Los Angeles County Warns of Cychlorphine After First Confirmed Fatal Overdose. After confirming the first fatal overdose in the county involving cychlorphine, a potent synthetic opioid, Los Angeles County health officials issued a warning last Thursday about the drug's presence in the illicit drug supply. Cychlorphine is an "orphine" opioid, distinct from fentanyl. UNODC reports breathing suppression in animal studies and detections in counterfeit medicines and drug mixtures; it is also sold by name, but it is unclear how often people knowingly use it. Although the warning about cychlorphine came last week, the death occurred in February, and it took until recently for the drug to be identified. Health officials warned that fentanyl test strips would not detect cychlorphine and suggested concerned residents take advantage of the county's free drug-checking services.
Australian Festival Drug Checking Finds High-Dose Ecstasy Tablets. New South Wales health officials issued an October 9 warning after the government’s drug-checking service detected high-dose MDMA tablets at Sydney’s Knockout Outdoor festival on October 3. They warned that potency can vary within the same batch and that dangerous tablets could be circulating in the state. The warning shows the value of drug checking in identifying unexpectedly strong substances and spreading the word.
UN Warns of PMMA in European Ecstasy Tablets. The United Nations Office on Drugs and Crime issued an October 6 alert about PMMA detected in tablets sold as ecstasy in seven European countries since July. Some contained more than 100 milligrams of PMMA. PMMA is an amphetamine-type stimulant more toxic than MDMA, with dangerous overheating among its risks, according to the BC Medical Journal. UNODC warned that because PMMA takes longer to take effect, people expecting MDMA might take additional doses before the effect of the initial dose is felt. The agency also cautioned that a tablet's color and markings cannot identify its contents, and recommended drug checking, lab testing, and international information-sharing to reduce risks.
Extrajudicial Killings
ICC Rejects Duterte Bid to Reframe Charges, Orders One Incident Removed. The VERA Files reported on October 10 that International Criminal Court (ICC) judges rejected a defense effort to require prosecutors to refile charges against former Philippine president Rodrigo Duterte on charges of crimes against humanity for murder and attempted murder in his bloody, years-long campaign against drug users and sellers. The court upheld the previously filed charges and allowed prosecutors to use additional incidents illustrating the alleged offenses but ordered them to remove one incident from their trial brief. In a separate decision, judges found Duterte fit to stand trial; the ICC’s October 8 announcement confirms that proceedings are scheduled to open November 30.
Human Rights Watch Details Abuses in US Maritime Operations Near Ecuador. In an October 2 report, Human Rights Watch (HRW) examined US operations against eight Ecuadorian fishing vessels, describing allegations of abuse against crew members and reporting judicial findings that the arrest of 56 crew members was illegal. HRW reported that the attacks took place between August 28 and September 16 and resulted in the detention of 140 out of 160 crew members, with some crew reporting beatings and threats in an effort to obtain confessions. The US has claimed the boats supplied fuel to drug traffickers, but neither it nor the Ecuadorian government has produced compelling evidence tying individual crew members to any crimes. HRW called for an investigation into the alleged abuses and the disclosure of the legal rationale behind the raids.
Amnesty International, Airwars and El CLIP have examined earlier incidents involving three fishing boats reportedly targeted through a covert CIA program. A June 11 congressional letter seeks answers about US involvement. Ecuadorian registration, if established, could provide a potential basis for ICC jurisdiction subject to other legal requirements. For related context on military abuses ashore, see Al Jazeera’s documentary Ecuador’s Disappeared.
Retired Coast Guard Officers Challenge Boat Strikes on Legal and Operational Grounds. In a September 2 analysis published in Just Security, three retired Coast Guard officers argue that the campaign of deadly strikes on alleged drug trafficking boats in the Caribbean and Eastern Pacific—there have been more than 70 attacks, with 238 people reported killed through October 4, including unrecovered survivors presumed dead, according to the WOLA data used in StoptheDrugWar.org’s charts—not only violates domestic and international law, but also undermines effective law enforcement. Stephen Chamberlin, Leanne Lusk, and Brian McNamara argue that killing suspects and destroying vessels eliminates opportunities to interview crews, collect evidence, and investigate the networks behind shipments. They note that maritime agreements and Coast Guard authorities permit boarding, arrest, and prosecution of suspected criminals. They also warn that lethal strikes jeopardize intelligence-sharing relationships and expose service members to legal and ethical risks.
For more on the legal and policy issues, see Just Security’s collection of analysis on US boat strikes and related operations.
International System
HRI Publishes Drug Policy Highlights from UN Human Rights Council Session. Harm Reduction International (HRI) published a written briefing on October 15 reviewing drug-policy debates and reports from the UN Human Rights Council’s September 7–October 7 session. It highlights a UN working group’s finding that about 45 percent of people charged with possession for personal use in Australia are prosecuted instead of diverted, as well as concerns about coercive drug courts and disproportionate imprisonment of Indigenous people.
The briefing also cites UN concerns about prolonged drug-related detention in Sri Lanka and how fear of arrest or losing child custody can keep women from seeking health services. Separately, HRI reports that Ambika Satkunanathan delivered a statement on its behalf during the session, urging reform of Sri Lanka’s punitive drug policies. The written briefing summarizes the session’s proceedings; it is not itself an oral presentation or a newly adopted global drug policy.
Additional items with an international focus appear in Drug Policy, Harm Reduction -- Medication Assisted Treatment, Harm Reduction - Drug Checking, and Extrajudicial Killings.
This work by StoptheDrugWar.org is licensed under Creative Commons Attribution-ShareAlike 4.0 International
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