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Methadone
and
Cipro:
Patients
Needing
Both
Should
Consult
Physicians
About
Possible
Drug
Interaction
11/9/01
According to an article published last
year in the British medical journal The Lancet, there is a significant
drug interaction between Ciprofloxacin (Cipro), used to prevent and treat
anthrax, and methadone, an opiate used to treat heroin addiction and severe
pain.
According to The Lancet, Cipro may inhibit
the primary enzyme responsible for metabolizing methadone, elevating methadone
levels significantly and creating a risk of overdose. This does not
mean that methadone patients cannot take Cipro, but it might mean they
need to lower their doses.
Any patient taking both methadone and Cipro
should discuss this possible interaction with their physician. It's
also recommended by that patients using LAAM and Cipro consult with their
physicians.
The Lancet article is "Methadone, Ciprofloxacin,
and Adverse Drug Reactions," by Karin Herrlin, Marta Segerdahi, Lars L
Gustafsson and Eija Kalso, Lancet 356:2069-70, 12/16/2000 Research Letters.
It can be read online by registering at thelancet.com and then visiting
http://www.thelancet.com/journal/vol356/iss9247/contents/
to download the document.
-- END --
|
Issue #210, 11/9/01
Proposed Marijuana Penalty Increase at Ohio University Meets Stiff Student Opposition | FDA Approves Study of Ecstasy as Treatment for Post-Traumatic Stress Disorder | School Drug Testing Headed for Supreme Court Again | Walters Drug Czar Nomination Approved in Senate Committee Vote | Ashcroft Sics DEA on Oregon Suicide Doctors | Drug Reformers, Colombia, and the Anti-Terrorism Act | Indonesia Marches Backward on Drug Policy | Election Report: New York City Drug Reformers, Virginia Reams Reeferendum Buried by Anthrax and Terrorist Attacks | Amnesty International Drug War Resolution Passes Northeast Regional Conference, Goes on to National Meeting | Methadone and Cipro: Patients Needing Both Should Consult Physicians About Possible Drug Interaction | Massive Military Presence and Abuses Continue in Bolivia's Chapare Region | Journal of Cannabis Therapeutics Online | Alerts: HEA Drug Provision, Drug Czar Nomination, DEA Hemp Ban, Ecstasy Bill, Mandatory Minimums, Medical Marijuana | The Reformer's Calendar
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