March 22, 1972: The Richard Nixon-appointed, 13-member National Commission on Marijuana and Drug Abuse recommends the decriminalization of marijuana, concluding, "Marihuana's relative potential for harm to the vast majority of individual users and its actual impact on society does not justify a social policy designed to seek out and firmly punish those who use it."

March 19, 1983: Best known for her role in Just Say No, First Lady Nancy Reagan appears on the NBC sitcom Diff'rent Strokes, declaring: "Let me tell you a true story about a boy we'll call Charlie. He was only 14 and he was burned out on marijuana... One day, when his little sister wouldn't steal some money for him to go and buy some more drugs, he brutally beat her. The real truth is there's no such thing as soft drugs and hard drugs. All drugs are dumb... Don't end up another Charlie."

March 23, 1983: Vice President George Herbert Walker Bush is placed in charge of the National Narcotics Border Interdiction System, which was supposed to staunch the drug flow over all US borders. Twenty-six years later drugs continue to be widely available throughout the United States.

March 25, 1994: Retired minister Accelyne Williams dies of a heart attack when a SWAT team consisting of 13 heavily armed Boston police officers raids his apartment based on an incorrect tip by an unidentified informant. No drugs or guns were found in the apartment. An editorial in The Boston Globe later observed: "The Williams tragedy resulted, in part, from the 'big score' mentality of the centralized Boston Police Drug Control Unit. Officers were pumped up to seize machine guns in addition to large quantities of cocaine and a 'crazy amount of weed,' in the words of the informant."

March 24, 1998: House Speaker Newt Gingrich (R-GA) establishes the Speaker's Task Force for a Drug-Free America to design a World War II-style victory plan to save America's children from illegal drugs and achieve a Drug-Free America by 2002. Eleven years after the founding of the task force, in 2009, drugs continue to be widely available throughout the United States.

March 19, 2001: Mexican President Vicente Fox is quoted in the Associated Press: "[T]he day that the alternative of freeing the consumption of drugs from punishment comes, it will have to be done in the entire world because we are not going to win anything if Mexico does it, but the production and traffic of the drugs... to the United States continues. Thus, humanity will one day view it [legalization] as the best in this sense."

March 20, 2002: Reuters reports that British scientists found that motorists who smoke a cannabis joint retain more control behind the wheel than those who drink a glass of wine. Research from Britain's Transport Research Laboratory showed drivers found it harder to maintain constant speed and road position after drinking the equivalent of a glass of wine than after smoking a "spliff."

March 25, 2002: The Maryland House of Delegates overwhelmingly approves H.B. 1222, the Darrell Putman Compassionate Use Act, which removes criminal penalties for the medical use of marijuana.

March 21, 2003: President Bush announces his intention to nominate Karen P. Tandy to be the Drug Enforcement Administration's new administrator. Tandy served in the Department of Justice (DOJ) as Associate Deputy Attorney General and Director of the Organized Crime Drug Enforcement Task Force. She also previously served in DOJ as Chief of Litigation in the Asset Forfeiture Office and as Deputy Chief for Narcotics and Dangerous Drugs. Earlier in her career, she prosecuted drug, money laundering, and forfeiture cases as an Assistant United States Attorney in the Eastern District of Virginia and in the Western District of Washington.