Cocaine Vaccine Backfires Horribly
I wonder if any of the researchers saw this coming:
Whoa, that's doesn't sound like any fun at all. I assume the researchers told these people not to bother increasing their dose. Stories like this are the reason I'm skeptical of drugs that block receptors for other drugs.
The vaccine, called TA-CD, shows promise but could also be dangerous; some of the addicts participating in a study of the vaccine started doing massive amounts of cocaine in hopes of overcoming its effects, according to Thomas R. Kosten, the lead researcher on the study, which was published in the Archives of General Psychiatry in October.
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Nobody overdosed, but some of them had 10 times more cocaine coursing through their systems than researchers had encountered before, according to Kosten. He said some of the addicts reported to researchers that they had gone broke buying cocaine from multiple drug dealers, hoping to find a variety that would get them high. [Washington Post]
Whoa, that's doesn't sound like any fun at all. I assume the researchers told these people not to bother increasing their dose. Stories like this are the reason I'm skeptical of drugs that block receptors for other drugs.
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