August 15, 1988: In his acceptance speech to the Republican National Convention, George Herbert Walker Bush states, "I want a drug-free America. Tonight, I challenge the young people of our country to shut down the drug dealers around the world... My Administration will be telling the dealers, 'Whatever we have to do, we'll do, but your day is over. You're history.'"

August 18, 1989: Luis Carlos Galan, a Colombian presidential candidate who spoke in favor of extradition, is assassinated at a campaign rally near Bogota. That evening, President Virgilio Barco Vargas issues an emergency decree reestablishing the policy of extradition. In response, the "Extraditables" declare all-out war against the Colombian government and begin a bombing/murder campaign that lasts until January 1991.

August 20, 1990: The US House of Representatives Committee on Government Operations releases a report on the results of Operation Snowcap, the Reagan-Bush administration program aimed at stopping the flow of drugs into the United States at their source. Snowcap's goal had been to eliminate coca crops, cocaine processing laboratories, clandestine landing strips, and other trafficking operations in the coca producing countries of South America. The report found that less than one percent of the region's cocaine had been destroyed by this campaign and that authorities in Bolivia, Peru, and Colombia were deeply involved in narcotics trafficking.

August 20, 1994: The Guardian reports that Raymond Kendall, secretary general of Interpol, said, "The prosecution of thousands of otherwise law-abiding citizens every year is both hypocritical and an affront to individual, civil, and human rights... Drug use should no longer be a criminal offense."

August 16, 1996: While visiting San Francisco, US drug czar Barry McCaffrey claims to media, "There is not a shred of scientific evidence that shows that smoked marijuana is useful or needed. This is not science. This is not medicine. This is a cruel hoax and sounds more like something out of a Cheech and Chong show." Advocates later point out that there is in fact scientific evidence supporting medical marijuana.

August 18, 1996: In San Francisco, a city church distributes marijuana to patients who possess a doctor's recommendation in wake of the temporary injunction closing the San Francisco Cannabis Buyers' Club. "I believe the moral stance [in this instance] is to break the law to make this marijuana available," said Rev. Jim Mitulski of the Metropolitan Community Church of San Francisco. "Our church's spiritual vitality has always come from a willingness to act where people have been reluctant to act. This is not a bystander church."

August 17, 1999: CNN reports that federal authorities say they are sweeping up the last few indicted members of a major drug trafficking network that shipped tons of mostly Colombian cocaine and marijuana throughout the United States. Nearly 100 suspects have been indicted in "Operation Southwest Express" and 77 have been arrested in raids in 14 cities.

August 19, 1999: Confronting questions about possible past drug use, Republican presidential candidate George W. Bush told reporters he had not used illegal drugs in 25 years, and added that if voters insisted on knowing more, "they can go find somebody else to vote for."

August 14, 2002: Twelve hundred medical marijuana patients, many suffering from life-threatening illnesses, lose their supply of medicine when Ontario police raid the Toronto Compassion Centre.