March 3, 1905: The first Congressional anti-drug law is passed when the US colonial government prohibits opium in the Philippines.

March 1, 1915: The Harrison Narcotics Act goes into legal effect, beginning federal prohibition of drugs.

March 4, 1992: George Bush's White House has bureaucrats terminate the federal government's Compassionate Investigational New Drug (IND) medical marijuana program, barring even approved patients from receiving marijuana and allowing only a small handful already receiving it to continue.

February 28, 1995: In compliance with the 1994 Crime Act, the US Sentencing Commission issues a report on the current federal structure of differing penalties on powder cocaine and crack cocaine, recommending that Congress "revisit" penalties enacted for those offenses.

February 29, 1996: In his State of the Union address, President Clinton nominates Army General Barry McCaffrey, a veteran of Vietnam and Desert Storm, as director of the Office of National Drug Control Policy. McCaffrey had been head of the US Southern Command (SouthCom) which provides military backup for US policy in Latin America -- a policy long linked with chronically ineffective and corrupt drug enforcement.

February 28, 1998: President Clinton recertifies Mexico as a fully cooperating ally in the struggle against drug smuggling despite a letter from 40 US senators urging Clinton to deny certification.

February 27, 1999: Conservative William F. Buckley, Jr. is quoted in the New York Post: "Even if one takes every reefer madness allegation of the prohibitionists at face value, prohibition has done far more harm to far more people than marijuana ever could."

March 1, 1999: The advice columnist Abigail Van Buren in her popular column "Dear Abby" says: "I agree that marijuana laws are overdue for an overhaul. I also favor the medical use of marijuana -- if it's prescribed by a physician. I cannot understand why the federal government should interfere with the doctor-patient relationship, nor why it would ignore the will of the majority of voters who have legally approved such legislation."

February 28, 2000: UPI reports that Spanish researchers said the chemical in marijuana that produces a "high" shows promise as a weapon against deadly brain tumors. A research team from Complutense University and Autonoma University in Madrid found that one of marijuana's active ingredients, THC, killed tumor cells in advanced cases of glioma, a quick-killing cancer for which there is currently no effective treatment.

March 1, 2004: The State Department releases its annual International Narcotics Control Strategy Report (INCSR) revealing that Afghanistan produced a larger poppy crop in 2003 than ever before. Some 61,000 hectares of land were cultivated with poppy in 2003 -- up almost twofold from about 31,000 hectares in 2002.