November 28, 1993: Reuters reports that Colombia's prosecutor general Gustavo de Greiff said the war on drugs has failed and Colombia should legalize cocaine and marijuana trafficking because the United States and Europe are decriminalizing consumption.

December 2, 1993: Notorious drug lord Pablo Escobar is hunted down and killed by Colombian police making use of US technology. At his funeral days later, tens of thousands of Medellin residents come out to mourn him.

December 3, 1998: Colombian police seize about seven tons of cocaine in Cartagena, Colombia, destined for the US via Cuba.

November 30, 2000: The DEA announces that it intends to prohibit hemp products, including shampoo, soap, and food made from non-psychoactive hemp seeds. (DEA loses this one.)

December 1, 2000: President of Uruguay Jorge Batlle is quoted in El Observador suggesting legalization of drugs.

November 30, 2001: The Austin Chronicle calls John Walters, the new US drug czar, "the Dr. Strangelove of our country's absurd drug war -- he dismisses anyone who says our nation's prisons are too full, he favors longer jail sentences for marijuana users, he has declared that there's too much 'treatment capacity' in the US, he opposes efforts to address the racial discrepancies in drug enforcement, he wants more militarization of the drug war at home and abroad, he'd like to see an expansion of our government's war in Colombia, and he's been a noisy opponent of state initiatives to allow the medical use of marijuana."

December 4, 2001: Canada's Auditor General releases a report on the federal government's role in dealing with illicit drugs. Part of the report reads: "Eleven federal departments and agencies are involved in the effort to control illicit drugs at a cost of about $500 million a year... But they don't know the extent of the problem and whether or not they are succeeding in their efforts."

December 2, 2002: Reuters reports that an independent study concluded marijuana use does not lead teenagers to experiment with hard drugs like heroin or cocaine. The study by the private, nonprofit RAND Drug Policy Research Center countered the theory that marijuana acts as a so-called gateway drug to more harmful narcotics, a key argument prohibitionists use against legalizing marijuana in the United States.

November 29, 2004: In the US Supreme Court, oral arguments are heard in the Gonzales v. Raich medical marijuana case.