October 22, 1982: The first publicly known case of contra cocaine shipments appears in government files in a cable from the CIA's Directorate of Operations. The cable passes on word that US law enforcement agencies are aware of "links between (a US religious organization) and two Nicaraguan counter-revolutionary groups [which] involve an exchange in (the United States) of narcotics for arms." [The material in parentheses was inserted by the CIA as part of its declassification of the cable. The name of the religious group remains secret.]

October 19, 1999: Taking a states' rights approach to medical marijuana, candidate George W. Bush says, "I believe each state can choose that decision as they so choose." As president, Bush instead escalates prosecutions of medical marijuana providers by the US Dept. of Justice and opposes states' rights arguments in court proceedings.

October 23, 2001: Britain's Home Secretary, David Blunkett, proposes the reclassification of cannabis from Class B to Class C. Cannabis is soon decriminalized in Great Britain, only to be returned to Class B by the Labor government in 2008.

October 17, 2002: Florida Governor Jeb Bush's daughter is sentenced to 10 days in jail and led away in handcuffs after being accused of having crack cocaine in her shoe while in drug rehab. In a statement, the governor says he realizes his daughter must face the consequences of her actions.

October 23, 2002: Time/CNN conducts a telephone poll of 1,007 adult Americans over two days (October 23-24). The result: Nearly one out of every two American adults acknowledges they have used marijuana, up from fewer than one in three in 1983.

October 20, 2004: A groundbreaking coalition of black professional organizations comes together to form the National African American Drug Policy Coalition (NAADPC). NAADPC "urgently seeks alternatives to misguided drug policies that have led to mass incarceration."